How does Olyset Plus work?
Olyset Plus Regeneration
Building on Olyset Net technology, liquid permethrin is released into tough polyethylene fibres, but with the addition of PBO to boost efficacy. The rate in which PBO and permethrin migrate from the fibre's internal reservoir to the surface of the net has been adjusted in Olyset Plus to provide rapid regeneration, making the net fully active again within 1-2 days after washing.
We believe that in areas where resistant mosquitoes have been found, rapid regeneration after washing of both synergist and insecticide is required to ensure that LLINs repel, kill and prevent mosquitos from biting adults and young children.
What is Piperonyl Butoxide?
Piperonyl butoxide (PBO) is a synergist which has been safely used for over 50 years to enhance the performance of pyrethroid insecticides, especially in household aerosols. When combined with permethrin, the protective effect of the insecticide is dramatically increased.
How does Piperonyl Butoxide combat resistance?
All insects, whether susceptible or resistant, have enzymes that can metabolise insecticides into harmless components. Some of these enzymes, known as cytochrome P450s, are powerful oxidising agents that can detoxify an active ingredient before the desired effect is achieved. By adding PBO, this action can be blocked. The synergist inhibits the breakdown or the metabolism of insecticides in resistant insects, rendering the insecticide more effective; while at the same time the activity of pyrethroids to susceptible insects is increased. For this reason, adding PBO to an LLIN is beneficial even in areas where there is no insecticide resistance.